Authors: Post, et al.
Title: Re-evaluating carbamazepine prophylaxis in bipolar disorder.
Reference: Br J Psychiatry 1997;170:202-4.
Publication type: Review.
Patients: Bipolar patients.
Treatment: Carbamazepine or Lithium.
Reviewer’s conclusions: Despite negative conclusions from a meta-analysis and reviews, there are a substantial number of controlled, partly controlled, and open studies that suggest the added value of carbamazepine in the maintenance treatment of bipolar patients. Nonetheless, some patients show loss of efficacy of carbamazepine (as well as valproate or lithium) during long-term follow up.